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1.

Inhaled Fluticasone Furoate for Outpatient Treatment of Covid-19.

Boulware, David R; Lindsell, Christopher J; Stewart, Thomas G; Hernandez, Adrian F; Collins, Sean; McCarthy, Matthew William; Jayaweera, Dushyantha; Gentile, Nina; Castro, Mario; Sulkowski, Mark; McTigue, Kathleen; Felker, G Michael; Ginde, Adit A; Dunsmore, Sarah E; Adam, Stacey J; DeLong, Allison; Hanna, George; Remaly, April; Thicklin, Florence; Wilder, Rhonda; Wilson, Sybil; Shenkman, Elizabeth; Naggie, Susanna.

N Engl J Med ; 389(12): 1085-1095, 2023 Sep 21.

Article in English | MEDLINE | ID: mdl-37733308

2.

Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19.

Bramante, Carolyn T; Huling, Jared D; Tignanelli, Christopher J; Buse, John B; Liebovitz, David M; Nicklas, Jacinda M; Cohen, Kenneth; Puskarich, Michael A; Belani, Hrishikesh K; Proper, Jennifer L; Siegel, Lianne K; Klatt, Nichole R; Odde, David J; Luke, Darlette G; Anderson, Blake; Karger, Amy B; Ingraham, Nicholas E; Hartman, Katrina M; Rao, Via; Hagen, Aubrey A; Patel, Barkha; Fenno, Sarah L; Avula, Nandini; Reddy, Neha V; Erickson, Spencer M; Lindberg, Sarah; Fricton, Regina; Lee, Samuel; Zaman, Adnin; Saveraid, Hanna G; Tordsen, Walker J; Pullen, Matthew F; Biros, Michelle; Sherwood, Nancy E; Thompson, Jennifer L; Boulware, David R; Murray, Thomas A.

N Engl J Med ; 387(7): 599-610, 2022 08 18.

Article in English | MEDLINE | ID: mdl-36070710

3.

Effect of Early Treatment with Ivermectin among Patients with Covid-19.

Reis, Gilmar; Silva, Eduardo A S M; Silva, Daniela C M; Thabane, Lehana; Milagres, Aline C; Ferreira, Thiago S; Dos Santos, Castilho V Q; Campos, Vitoria H S; Nogueira, Ana M R; de Almeida, Ana P F G; Callegari, Eduardo D; Neto, Adhemar D F; Savassi, Leonardo C M; Simplicio, Maria I C; Ribeiro, Luciene B; Oliveira, Rosemary; Harari, Ofir; Forrest, Jamie I; Ruton, Hinda; Sprague, Sheila; McKay, Paula; Guo, Christina M; Rowland-Yeo, Karen; Guyatt, Gordon H; Boulware, David R; Rayner, Craig R; Mills, Edward J.

N Engl J Med ; 386(18): 1721-1731, 2022 05 05.

Article in English | MEDLINE | ID: mdl-35353979

4.

Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.

Jarvis, Joseph N; Lawrence, David S; Meya, David B; Kagimu, Enock; Kasibante, John; Mpoza, Edward; Rutakingirwa, Morris K; Ssebambulidde, Kenneth; Tugume, Lillian; Rhein, Joshua; Boulware, David R; Mwandumba, Henry C; Moyo, Melanie; Mzinganjira, Henry; Kanyama, Cecilia; Hosseinipour, Mina C; Chawinga, Chimwemwe; Meintjes, Graeme; Schutz, Charlotte; Comins, Kyla; Singh, Achita; Muzoora, Conrad; Jjunju, Samuel; Nuwagira, Edwin; Mosepele, Mosepele; Leeme, Tshepo; Siamisang, Keatlaretse; Ndhlovu, Chiratidzo E; Hlupeni, Admire; Mutata, Constantine; van Widenfelt, Erik; Chen, Tao; Wang, Duolao; Hope, William; Boyer-Chammard, Timothée; Loyse, Angela; Molloy, Síle F; Youssouf, Nabila; Lortholary, Olivier; Lalloo, David G; Jaffar, Shabbar; Harrison, Thomas S.

N Engl J Med ; 386(12): 1109-1120, 2022 03 24.

Article in English | MEDLINE | ID: mdl-35320642

5.

Diagnosis and management of cryptococcal meningitis in HIV-infected adults.

McHale, Thomas C; Boulware, David R; Kasibante, John; Ssebambulidde, Kenneth; Skipper, Caleb P; Abassi, Mahsa.

Clin Microbiol Rev ; 36(4): e0015622, 2023 12 20.

Article in English | MEDLINE | ID: mdl-38014977

6.

Favorable Antiviral Effect of Metformin on Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of Coronavirus Disease 2019.

Bramante, Carolyn T; Beckman, Kenneth B; Mehta, Tanvi; Karger, Amy B; Odde, David J; Tignanelli, Christopher J; Buse, John B; Johnson, Darrell M; Watson, Ray H B; Daniel, Jerry J; Liebovitz, David M; Nicklas, Jacinda M; Cohen, Ken; Puskarich, Michael A; Belani, Hrishikesh K; Siegel, Lianne K; Klatt, Nichole R; Anderson, Blake; Hartman, Katrina M; Rao, Via; Hagen, Aubrey A; Patel, Barkha; Fenno, Sarah L; Avula, Nandini; Reddy, Neha V; Erickson, Spencer M; Fricton, Regina D; Lee, Samuel; Griffiths, Gwendolyn; Pullen, Matthew F; Thompson, Jennifer L; Sherwood, Nancy E; Murray, Thomas A; Rose, Michael R; Boulware, David R; Huling, Jared D.

Clin Infect Dis ; 2024 May 01.

Article in English | MEDLINE | ID: mdl-38690892

7.

Complex Decisions in HIV-Related Cryptococcosis: Addressing Second Episodes of Cryptococcal Meningitis.

Musubire, Abdu; Kagimu, Enock; Mugabi, Timothy; Meya, David B; Boulware, David R; Bahr, Nathan C.

Curr HIV/AIDS Rep ; 21(2): 75-85, 2024 Apr.

Article in English | MEDLINE | ID: mdl-38400871

8.

Oral Fluvoxamine With Inhaled Budesonide for Treatment of Early-Onset COVID-19 : A Randomized Platform Trial.

Reis, Gilmar; Dos Santos Moreira Silva, Eduardo Augusto; Medeiros Silva, Daniela Carla; Thabane, Lehana; de Souza Campos, Vitoria Helena; Ferreira, Thiago Santiago; Quirino Dos Santos, Castilho Vitor; Ribeiro Nogueira, Ana Maria; Figueiredo Guimaraes Almeida, Ana Paula; Cançado Monteiro Savassi, Leonardo; de Figueiredo Neto, Adhemar Dias; Bitarães, Carina; Cruz Milagres, Aline; Diniz Callegari, Eduardo; Campos Simplicio, Maria Izabel; Barra Ribeiro, Luciene; Oliveira, Rosemary; Harari, Ofir; Wilson, Lindsay A; Forrest, Jamie I; Ruton, Hinda; Sprague, Sheila; McKay, Paula; Guo, Christina M; Guyatt, Gordon H; Rayner, Craig R; Boulware, David R; Ezer, Nicole; Lee, Todd C; McDonald, Emily Gibson; Bafadhel, Mona; Butler, Christopher; Rodrigues Silva, Josue; Dybul, Mark; Mills, Edward J.

Ann Intern Med ; 176(5): 667-675, 2023 05.

Article in English | MEDLINE | ID: mdl-37068273

9.

How Applicable Is the Single-Dose AMBITION Regimen for Human Immunodeficiency Virus-Associated Cryptococcal Meningitis to High-Income Settings?

Harrison, Thomas S; Lawrence, David S; Mwandumba, Henry C; Boulware, David R; Hosseinipour, Mina C; Lortholary, Olivier; Meintjes, Graeme; Mosepele, Mosepele; Jarvis, Joseph N.

Clin Infect Dis ; 76(5): 944-949, 2023 03 04.

Article in English | MEDLINE | ID: mdl-36166405

10.

Effect of Coronavirus Disease 2019 Lockdowns on Identification of Advanced Human Immunodeficiency Virus Disease in Outpatient Clinics in Uganda.

Nalintya, Elizabeth; Sekar, Preethiya; Kavuma, Paul; Kigozi, Joanita; Ssuna, Martin; Kirumira, Paul; Naluyima, Rose; Namuli, Teopista; Musa, Fred Turya; Skipper, Caleb P; Hullsiek, Kathy Huppler; Ellis, Jayne; Boulware, David R; Meya, David B; Rajasingham, Radha.

Clin Infect Dis ; 76(11): 2014-2017, 2023 06 08.

Article in English | MEDLINE | ID: mdl-36799434

11.

Outpatient Cryptococcal Antigen Screening Is Associated With Favorable Baseline Characteristics and Improved Survival in Persons With Cryptococcal Meningitis in Uganda.

Levin, Anna E; Bangdiwala, Ananta S; Nalintya, Elizabeth; Kagimu, Enock; Kasibante, John; Rutakingirwa, Morris K; Mpoza, Edward; Jjunju, Samuel; Nuwagira, Edwin; Naluyima, Rose; Kirumira, Paul; Hou, Cody; Ssebambulidde, Kenneth; Musubire, Abdu K; Williams, Darlisha A; Abassi, Mahsa; Muzoora, Conrad; Hullsiek, Katherine H; Rajasingham, Radha; Meya, David B; Boulware, David R; Skipper, Caleb P.

Clin Infect Dis ; 76(3): e759-e765, 2023 02 08.

Article in English | MEDLINE | ID: mdl-35859045

12.

Recurrence of Symptoms Following Cryptococcal Meningitis: Characterizing a Diagnostic Conundrum With Multiple Etiologies.

Bahr, Nathan C; Skipper, Caleb P; Huppler-Hullsiek, Kathy; Ssebambulidde, Kenneth; Morawski, Bozena M; Engen, Nicole W; Nuwagira, Edwin; Quinn, Carson M; Ramachandran, Prashanth S; Evans, Emily E; Lofgren, Sarah M; Abassi, Mahsa; Muzoora, Conrad; Wilson, Michael R; Meya, David B; Rhein, Joshua; Boulware, David R.

Clin Infect Dis ; 76(6): 1080-1087, 2023 03 21.

Article in English | MEDLINE | ID: mdl-36303432

13.

Oral Lipid Nanocrystal Amphotericin B for Cryptococcal Meningitis: A Randomized Clinical Trial.

Boulware, David R; Atukunda, Mucunguzi; Kagimu, Enock; Musubire, Abdu K; Akampurira, Andrew; Tugume, Lillian; Ssebambulidde, Kenneth; Kasibante, John; Nsangi, Laura; Mugabi, Timothy; Gakuru, Jane; Kimuda, Sarah; Kasozi, Derrick; Namombwe, Suzan; Turyasingura, Isaac; Rutakingirwa, Morris K; Mpoza, Edward; Kigozi, Enos; Muzoora, Conrad; Ellis, Jayne; Skipper, Caleb P; Matkovits, Theresa; Williamson, Peter R; Williams, Darlisha A; Fieberg, Ann; Hullsiek, Kathy H; Abassi, Mahsa; Dai, Biyue; Meya, David B.

Clin Infect Dis ; 77(12): 1659-1667, 2023 12 15.

Article in English | MEDLINE | ID: mdl-37606364

14.

Single High Dose of Liposomal Amphotericin B in Human Immunodeficiency Virus/AIDS-Related Disseminated Histoplasmosis: A Randomized Trial.

Pasqualotto, Alessandro C; Lana, Daiane Dalla; Godoy, Cassia S M; Leitão, Terezinha do Menino Jesus Silva; Bay, Monica B; Damasceno, Lisandra Serra; Soares, Renata B A; Kist, Roger; Silva, Larissa R; Wiltgen, Denusa; Melo, Marineide; Guimarães, Taiguara F; Guimarães, Marilia R; Vechi, Hareton T; de Mesquita, Jacó R L; Monteiro, Gloria Regina de G; Adenis, Antoine; Bahr, Nathan C; Spec, Andrej; Boulware, David R; Israelski, Dennis; Chiller, Tom; Falci, Diego R.

Clin Infect Dis ; 77(8): 1126-1132, 2023 10 13.

Article in English | MEDLINE | ID: mdl-37232940

15.

Impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccination and Booster on Coronavirus Disease 2019 (COVID-19) Symptom Severity Over Time in the COVID-OUT Trial.

Boulware, David R; Murray, Thomas A; Proper, Jennifer L; Tignanelli, Christopher J; Buse, John B; Liebovitz, David M; Nicklas, Jacinda M; Cohen, Kenneth; Puskarich, Michael A; Belani, Hrishikesh K; Siegel, Lianne K; Klatt, Nichole R; Odde, David J; Karger, Amy B; Ingraham, Nicholas E; Hartman, Katrina M; Rao, Via; Hagen, Aubrey A; Patel, Barkha; Fenno, Sarah L; Avula, Nandini; Reddy, Neha V; Erickson, Spencer M; Lindberg, Sarah; Fricton, Regina; Lee, Samuel; Zaman, Adnin; Saveraid, Hanna G; Tordsen, Walker J; Pullen, Matthew F; Sherwood, Nancy E; Huling, Jared D; Bramante, Carolyn T.

Clin Infect Dis ; 76(3): e1-e9, 2023 02 08.

Article in English | MEDLINE | ID: mdl-36124697

16.

A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19.

Boulware, David R; Pullen, Matthew F; Bangdiwala, Ananta S; Pastick, Katelyn A; Lofgren, Sarah M; Okafor, Elizabeth C; Skipper, Caleb P; Nascene, Alanna A; Nicol, Melanie R; Abassi, Mahsa; Engen, Nicole W; Cheng, Matthew P; LaBar, Derek; Lother, Sylvain A; MacKenzie, Lauren J; Drobot, Glen; Marten, Nicole; Zarychanski, Ryan; Kelly, Lauren E; Schwartz, Ilan S; McDonald, Emily G; Rajasingham, Radha; Lee, Todd C; Hullsiek, Kathy H.

N Engl J Med ; 383(6): 517-525, 2020 08 06.

Article in English | MEDLINE | ID: mdl-32492293

17.

Advancing Diagnosis and Treatment in People Living with HIV and Tuberculosis Meningitis.

Kimuda, Sarah; Kasozi, Derrick; Namombwe, Suzan; Gakuru, Jane; Mugabi, Timothy; Kagimu, Enock; Rutakingirwa, Morris K; Leon, Kristoffer E; Chow, Felicia; Wasserman, Sean; Boulware, David R; Cresswell, Fiona V; Bahr, Nathan C.

Curr HIV/AIDS Rep ; 20(6): 379-393, 2023 Dec.

Article in English | MEDLINE | ID: mdl-37947980

18.

Differences in Reasons for Late Presentation to HIV Care in Uganda Among Men and Women.

Lofgren, Sarah M; Tsui, Sharon; Natala, Nakita; Nakasujja, Noeline; Sebuliba, Raymond; Ndyetukira, Jane Francis; Arinda, Anita; Akinyange, Vanessa; Hullsiek, Kathy H; Nalintya, Elizabeth; Sadiq, Alisat; Pastick, Katelyn A; Stadleman, Anna; Meya, David; Boulware, David R.

AIDS Behav ; 27(1): 303-313, 2023 Jan.

Article in English | MEDLINE | ID: mdl-35916948

19.

Effect of Fluvoxamine vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial.

McCarthy, Matthew W; Naggie, Susanna; Boulware, David R; Lindsell, Christopher J; Stewart, Thomas G; Felker, G Michael; Jayaweera, Dushyantha; Sulkowski, Mark; Gentile, Nina; Bramante, Carolyn; Singh, Upinder; Dolor, Rowena J; Ruiz-Unger, Juan; Wilson, Sybil; DeLong, Allison; Remaly, April; Wilder, Rhonda; Collins, Sean; Dunsmore, Sarah E; Adam, Stacey J; Thicklin, Florence; Hanna, George; Ginde, Adit A; Castro, Mario; McTigue, Kathleen; Shenkman, Elizabeth; Hernandez, Adrian F.

JAMA ; 329(4): 296-305, 2023 01 24.

Article in English | MEDLINE | ID: mdl-36633838

20.

Higher-Dose Fluvoxamine and Time to Sustained Recovery in Outpatients With COVID-19: The ACTIV-6 Randomized Clinical Trial.

Stewart, Thomas G; Rebolledo, Paulina A; Mourad, Ahmad; Lindsell, Christopher J; Boulware, David R; McCarthy, Matthew W; Thicklin, Florence; Garcia Del Sol, Idania T; Bramante, Carolyn T; Lenert, Leslie A; Lim, Stephen; Williamson, John C; Cardona, Orlando Quintero; Scott, Jake; Schwasinger-Schmidt, Tiffany; Ginde, Adit A; Castro, Mario; Jayaweera, Dushyantha; Sulkowski, Mark; Gentile, Nina; McTigue, Kathleen; Felker, G Michael; DeLong, Allison; Wilder, Rhonda; Rothman, Russell L; Collins, Sean; Dunsmore, Sarah E; Adam, Stacey J; Hanna, George J; Shenkman, Elizabeth; Hernandez, Adrian F; Naggie, Susanna.

JAMA ; 330(24): 2354-2363, 2023 12 26.

Article in English | MEDLINE | ID: mdl-37976072

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